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SORL1

Official Full Name
sortilin related receptor 1
Organism
Homo sapiens
GeneID
6653
Background
This gene encodes a mosaic protein that belongs to at least two families: the vacuolar protein sorting 10 (VPS10) domain-containing receptor family, and the low density lipoprotein receptor (LDLR) family. The encoded protein also contains fibronectin type III repeats and an epidermal growth factor repeat. The encoded preproprotein is proteolytically processed to generate the mature receptor, which likely plays roles in endocytosis and sorting. Mutations in this gene may be associated with Alzheimer's disease. [provided by RefSeq, Feb 2016]
Synonyms
LR11; LRP9; SORLA; gp250; SorLA-1; C11orf32;

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