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SNAI2

Official Full Name
snail family transcriptional repressor 2
Organism
Homo sapiens
GeneID
6591
Background
This gene encodes a member of the Snail family of C2H2-type zinc finger transcription factors. The encoded protein acts as a transcriptional repressor that binds to E-box motifs and is also likely to repress E-cadherin transcription in breast carcinoma. This protein is involved in epithelial-mesenchymal transitions and has antiapoptotic activity. Mutations in this gene may be associated with sporatic cases of neural tube defects. [provided by RefSeq, Jul 2008]
Synonyms
SLUG; WS2D; SLUGH; SLUGH1; SNAIL2;

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