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smyhc1


Official Full Name
slow myosin heavy chain 1
Organism
Danio rerio
Gene ID
321552
Background
Predicted to enable actin filament binding activity and microfilament motor activity. Acts upstream of or within several processes, including regulation of myofibril size; slow-twitch skeletal muscle fiber contraction; and striated muscle cell development. Predicted to be part of myosin II complex. Predicted to be active in cytoplasm and myosin filament. Is expressed in cardiovascular system; musculature system; paraxial mesoderm; and somite. Used to study distal arthrogryposis and spondylocarpotarsal synostosis syndrome. Human ortholog(s) of this gene implicated in atrial heart septal defect (multiple); heart conduction disease (multiple); and intrinsic cardiomyopathy (multiple). Orthologous to human MYH6 (myosin heavy chain 6). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
fb18g10; im:6897999; wu:fb18g10

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