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SMURF2

Official Full Name
SMAD specific E3 ubiquitin protein ligase 2
Organism
Homo sapiens
GeneID
64750
Background
Enables SMAD binding activity; identical protein binding activity; and ubiquitin protein ligase activity. Involved in negative regulation of transforming growth factor beta receptor signaling pathway; positive regulation of trophoblast cell migration; and ubiquitin-dependent protein catabolic process. Located in nuclear speck. Part of ubiquitin ligase complex. [provided by Alliance of Genome Resources, Feb 2025]

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