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smarca4a

Official Full Name
SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4a
Organism
Danio rerio
GeneID
353295
Background
Predicted to enable DNA binding activity; chromatin binding activity; and nucleosome array spacer activity. Acts upstream of or within several processes, including camera-type eye development; heart development; and nervous system development. Predicted to be part of SWI/SNF complex. Predicted to be active in chromatin and nucleus. Is expressed in several structures, including hematopoietic multipotent progenitor cell; mesoderm; nervous system; pectoral fin; and presumptive neural retina. Human ortholog(s) of this gene implicated in Coffin-Siris syndrome 4; hepatocellular carcinoma; lung non-small cell carcinoma; and rhabdoid tumor predisposition syndrome 2. Orthologous to human SMARCA4 (SWI/SNF related BAF chromatin remodeling complex subunit ATPase 4). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
brg1; smarca2; smarca4; wu:fb51a08;

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