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SLPI

Official Full Name
secretory leukocyte peptidase inhibitor
Organism
Homo sapiens
GeneID
6590
Background
This gene encodes a secreted inhibitor which protects epithelial tissues from serine proteases. It is found in various secretions including seminal plasma, cervical mucus, and bronchial secretions, and has affinity for trypsin, leukocyte elastase, and cathepsin G. Its inhibitory effect contributes to the immune response by protecting epithelial surfaces from attack by endogenous proteolytic enzymes. This antimicrobial protein has antibacterial, antifungal and antiviral activity. [provided by RefSeq, Nov 2014]
Synonyms
ALP; MPI; ALK1; BLPI; HUSI; WAP4; WFDC4; HUSI-I;

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