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SLIT2


Official Full Name
slit guidance ligand 2
Organism
Homo sapiens
Gene ID
9353
Background
This gene encodes a member of the slit family of secreted glycoproteins, which are ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. Members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Proteolytic processing of this protein gives rise to an N-terminal fragment that contains the four leucine-rich repeats and five epidermal growth factor repeats and a C-terminal fragment that contains four epidermal growth factor repeats and the cysteine knot. Both full length and cleaved proteins are secreted extracellularly and can function in axon repulsion as well as other specific processes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Synonyms
SLIL3; Slit-2

Cat.No. Product Name Price
SHL014142 shRNA set against Human SLIT2(NM_004787.1) Inquiry
SHW003579 shRNA set against Chicken SLIT2 (NM_001267075) Inquiry
SHH412692 shRNA set against Human SLIT2 (NM_004787.1) Inquiry
SHH412696 shRNA set against Mouse SLIT2 (NM_178804.3) Inquiry
SHH412700 shRNA set against Rat SLIT2 (NM_022632.2) Inquiry
SHL014088 shRNA set against Mouse Slit2(NM_178804.3) Inquiry
SHW015141 shRNA set against Danio rerio SLIT2 (NM_131735) Inquiry
Cat.No. Product Name Price
CDFH018080 Human SLIT2 cDNA Clone(NM_004787.1) Inquiry
CDFL012683 Mouse Slit2 cDNA Clone(NM_178804.3) Inquiry
MiUTR1H-09620 SLIT2 miRNA 3'UTR clone Inquiry
MiUTR1M-10962 SLIT2 miRNA 3'UTR clone Inquiry
CDCB165054 Chicken SLIT2 ORF Clone (NM_001267075) Inquiry
CDCB176616 Danio rerio SLIT2 ORF Clone (NM_131735) Inquiry
CDCB188903 Rabbit SLIT2 ORF clone (XM_008274523.1) Inquiry
CDCH083208 human SLIT2 ORF clone (NM_004787.1) Inquiry
CDCH401297 Rat SLIT2 ORF clone(NM_022632.2) Inquiry
CDCL186226 Mouse SLIT2 ORF clone(NM_178804.3) Inquiry
CDCS411958 Human SLIT2 ORF Clone (BC117190) Inquiry
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