This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.
SLC25A5; solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5; ANT2; ADP/ATP translocase 2; 2F1; T2; T3; ANT 2; ADP/ATP carrier protein; ADP,ATP carrier protein 2; solute carrier family 25 member 5; ADP,ATP carrier p; ADP,ATP carrier protein, fibroblast isoform; adenine nucleotide translocator 2 (fibroblast); AAC2; CHUNP6931; sr:nyz040; wu:fe06b05; SI:bZ46J2.1; SI:bZ46J2.3; SI:bZ46J2.5; SI:bZ46J2.6; SI:bZ46J2.7; SI:bZ46J2.9; si:bz46j2.2; solut