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SIPA1L3


Official Full Name
signal induced proliferation associated 1 like 3
Organism
Homo sapiens
Gene ID
23094
Background
This gene belongs to the signal induced proliferation associated 1 family of genes, which encode GTPase-activating proteins specific for the GTP-binding protein Rap1. Rap1 has been implicated in regulation of cell adhesion, cell polarity, and organization of the cytoskeleton. Like other members of the family, the protein encoded by this gene contains RapGAP and PDZ domains. In addition, this protein contains a C-terminal leucine zipper domain. This gene is proposed to function in epithelial cell morphogenesis and establishment or maintenance of polarity. Consistently, expression of the protein in cell culture showed localization to cell-cell borders in apical regions, and downregulation of the gene in 3D Caco2 cell culture resulted in abnormal cell polarity and morphogenesis. Allelic variants of this gene have been associated with congenital cataracts in humans. [provided by RefSeq, Feb 2016]
Synonyms
SPAL3; SPAR3; CTRCT45

Cat.No. Product Name Price
SHH407680 shRNA set against Human SIPA1L3 (NM_015073.1) Inquiry
SHH407684 shRNA set against Mouse SIPA1L3 (NM_001081028.1) Inquiry
SHH407688 shRNA set against Rat SIPA1L3 (NM_001013066.1) Inquiry
SHR226104 shRNA set against Rat Sipa1l3(NM_001013066.1) Inquiry
SHR226157 shRNA set against Human SIPA1L3(NM_015073.1) Inquiry
SHR226200 shRNA set against Mouse Sipa1l3(NM_001081028.1) Inquiry
Cat.No. Product Name Price
CDFG018798 Mouse Sipa1l3 cDNA Clone(NM_001081028.1) Inquiry
CDFH017587 Human SIPA1L3 cDNA Clone(NM_015073.1) Inquiry
CDFR002794 Rat Sipa1l3 cDNA Clone(NM_001013066.1) Inquiry
MiUTR1H-09407 SIPA1L3 miRNA 3'UTR clone Inquiry
MiUTR1M-10712 SIPA1L3 miRNA 3'UTR clone Inquiry
MiUTR1R-07352 SIPA1L3 miRNA 3'UTR clone Inquiry
CDCB186050 Rabbit SIPA1L3 ORF clone (XM_008257241.1) Inquiry
CDCH080340 human SIPA1L3 ORF clone (NM_015073.1) Inquiry
CDCH080342 Mouse Sipa1l3 ORF clone (NM_001081028.1) Inquiry
CDCR369794 Rat Sipa1l3 ORF Clone(NM_001013066.1) Inquiry
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