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shha

Official Full Name
sonic hedgehog signaling molecule a
Organism
Danio rerio
GeneID
30269
Background
Predicted to enable several functions, including calcium ion binding activity; cholesterol-protein transferase activity; and patched binding activity. Acts upstream of or within several processes, including embryonic organ development; fin development; and nervous system development. Predicted to be located in Golgi apparatus and endoplasmic reticulum. Predicted to be active in extracellular space. Is expressed in several structures, including central nervous system; digestive system; fin; head; and mesoderm. Human ortholog(s) of this gene implicated in several diseases, including Hirschsprung's disease; holoprosencephaly (multiple); hypoplastic or aplastic tibia with polydactyly; middle cerebral artery infarction; and polydactyly (multiple). Orthologous to human SHH (sonic hedgehog signaling molecule). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
shh; syu; vhh1; ShhNC; vhh-1; fc83d08; wu:fc83d08;

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