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SFTPC


Official Full Name
surfactant protein C
Organism
Homo sapiens
Gene ID
6440
Background
This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]
Synonyms
SP5; SP-C; PSP-C; SFTP2; SMDP2; BRICD6

Cat.No. Product Name Price
SHH406076 shRNA set against Human SFTPC (NM_003018.3) Inquiry
SHH406080 shRNA set against Mouse SFTPC (NM_011359.2) Inquiry
Cat.No. Product Name Price
CDCH079410 human SFTPC ORF clone (NM_001172357.1) Inquiry
CDCR356498 Human SFTPC ORF Clone(NM_001172410.1) Inquiry
CDFH017385 Human SFTPC cDNA Clone(NM_001172410.1) Inquiry
CDFH017386 Human SFTPC cDNA Clone(NM_001172357.1) Inquiry
MiUTR1H-09340 SFTPC miRNA 3'UTR clone Inquiry
CDCB159787 Human SFTPC ORF clone (BC005913) Inquiry
CDCB180279 Rabbit SFTPC ORF clone (XM_008249865.1) Inquiry
CDCH079408 human SFTPC ORF clone (NM_003018.3) Inquiry
CDCR250581 Mouse Sftpc ORF Clone(NM_011359.2) Inquiry
CDCR378441 Rat Sftpc ORF Clone(NM_017342.2) Inquiry
CDCS409000 Human SFTPC ORF Clone (BC005913) Inquiry
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