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SFPQ

Official Full Name
splicing factor proline and glutamine rich
Organism
Homo sapiens
GeneID
6421
Background
Enables DNA binding activity; histone deacetylase binding activity; and protein homodimerization activity. Involved in several processes, including alternative mRNA splicing, via spliceosome; positive regulation of oxidative stress-induced intrinsic apoptotic signaling pathway; and regulation of transcription by RNA polymerase II. Acts upstream of or within double-strand break repair via homologous recombination. Located in chromatin; nuclear matrix; and paraspeckles. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
PSF; POMP100; PPP1R140;

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