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SERPING1

Official Full Name
serpin family G member 1
Organism
Homo sapiens
GeneID
710
Background
This gene encodes a highly glycosylated plasma protein involved in the regulation of the complement cascade. Its encoded protein, C1 inhibitor, inhibits activated C1r and C1s of the first complement component and thus regulates complement activation. It is synthesized in the liver, and its deficiency is associated with hereditary angioneurotic oedema (HANE). Alternative splicing results in multiple transcript variants encoding the same isoform. [provided by RefSeq, May 2020]
Synonyms
C1IN; C1NH; HAE1; HAE2; C1INH;

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