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SERPINB8

Official Full Name
serpin family B member 8
Organism
Homo sapiens
GeneID
5271
Background
The protein encoded by this gene is a member of the ov-serpin family of serine protease inhibitors. The encoded protein is produced by platelets and can bind to and inhibit the function of furin, a serine protease involved in platelet functions. In addition, this protein has been found to enhance the mechanical stability of cell-cell adhesion in the skin, and defects in this gene have been associated with an autosomal-recessive form of exfoliative ichthyosis. [provided by RefSeq, Jan 2017]
Synonyms
PI8; CAP2; PI-8; PSS5; C18orf53;

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