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SERPINB4

Official Full Name
serpin family B member 4
Organism
Homo sapiens
GeneID
6318
Background
The protein encoded by this gene is a member of the serpin family of serine protease inhibitors. The encoded protein is highly expressed in many tumor cells and can inactivate granzyme M, an enzyme that kills tumor cells. This protein, along with serpin B3, can be processed into smaller fragments that aggregate to form an autoantigen in psoriasis, probably by causing chronic inflammation. [provided by RefSeq, Jan 2017]
Synonyms
PI11; SCCA1; SCCA2; LEUPIN; SCCA-2;

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