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Serpina1b


Official Full Name
serine (or cysteine) preptidase inhibitor, clade A, member 1B
Organism
Mus musculus
Gene ID
20701
Background
Enables serine-type endopeptidase inhibitor activity. Acts upstream of or within several processes, including in utero embryonic development; protein N-linked glycosylation; and response to peptide hormone. Located in extracellular region. Is expressed in gut; liver lobe; nucleus pulposus; and renal calyx. Human ortholog(s) of this gene implicated in several diseases, including alpha 1-antitrypsin deficiency; artery disease (multiple); chronic obstructive pulmonary disease (multiple); inflammatory bowel disease (multiple); and liver disease (multiple). Orthologous to human SERPINA1 (serpin family A member 1). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
PI2; Dom2; Spi1-2; D12Ucla2

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