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SEPT5


Official Full Name
septin 5
Organism
Homo sapiens
Gene ID
5413
Background
This gene is a member of the septin gene family of nucleotide binding proteins, originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast, Drosophila, and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11, the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib), whereby larger, non-coding transcripts are produced. [provided by RefSeq, Dec 2010]
Synonyms
SEPTIN5; H5; SEPT5; CDCREL; PNUTL1; CDCREL1; CDCREL-1; Septin-5; HCDCREL-1

Cat.No. Product Name Price
SHG011585 shRNA set against Rat Sept5(NM_053931.3) Inquiry
SHH404648 shRNA set against Human SEPT5 (NM_002688.5) Inquiry
SHH404652 shRNA set against Rat SEPT5 (NM_053931.3) Inquiry
SHR215444 shRNA set against Mouse Sept5(NM_213614.2) Inquiry
SHW001302 shRNA set against Chicken 41887 (NM_001030654) Inquiry
Cat.No. Product Name Price
CDFR013643 Rat Sept5 cDNA Clone(NM_053931.3) Inquiry
MiUTR1M-10560 SEPT5 miRNA 3'UTR clone Inquiry
MiUTR1R-07266 SEPT5 miRNA 3'UTR clone Inquiry
MiUTR4H-TG07927 SEPT5 miRNA 3'UTR clone Inquiry
CDCB162777 Chicken SEPT5 ORF Clone (NM_001030654) Inquiry
CDCR277674 Mouse Sept5 ORF Clone(NM_213614.2) Inquiry
CDCR380516 Rat Sept5 ORF Clone(NM_053931.3) Inquiry
CDCS419499 Human SEPT5 ORF Clone (BC025261) Inquiry
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