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SEPHS2


Official Full Name
selenophosphate synthetase 2
Organism
Homo sapiens
Gene ID
22928
Background
This gene encodes an enzyme that catalyzes the production of monoselenophosphate (MSP) from selenide and ATP. MSP is the selenium donor required for synthesis of selenocysteine (Sec), which is co-translationally incorporated into selenoproteins at in-frame UGA codons that normally signal translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is itself a selenoprotein containing a Sec residue at its active site, suggesting the existence of an autoregulatory mechanism. It is preferentially expressed in tissues implicated in the synthesis of selenoproteins and in sites of blood cell development. A pseudogene for this locus has been identified on chromosome 5. [provided by RefSeq, May 2017]
Synonyms
SPS2

Cat.No. Product Name Price
SHH404560 shRNA set against Human SEPHS2 (NM_012248.2) Inquiry
SHH404564 shRNA set against Mouse SEPHS2 (NM_009266.3) Inquiry
SHH404568 shRNA set against Rat SEPHS2 (NM_001079889.2) Inquiry
SHR214976 shRNA set against Human SEPHS2(NM_012248.2) Inquiry
SHR215040 shRNA set against Mouse Sephs2(NM_009266.3) Inquiry
SHR215058 shRNA set against Rat Sephs2(NM_001079889.2) Inquiry
Cat.No. Product Name Price
CDCS413261 Human SEPHS2 ORF Clone (BC002381) Inquiry
CDFH017196 Human SEPHS2 cDNA Clone(NM_012248.2) Inquiry
CDFH017197 Human SEPHS2 cDNA Clone(NM_012248.2) Inquiry
CDFR005044 Rat Sephs2 cDNA Clone(NM_001079889.2) Inquiry
MiUTR1H-09270 SEPHS2 miRNA 3'UTR clone Inquiry
MiUTR1M-10552 SEPHS2 miRNA 3'UTR clone Inquiry
MiUTR1R-07260 SEPHS2 miRNA 3'UTR clone Inquiry
CDCB191028 Rabbit SEPHS2 ORF clone (NM_001256961.1) Inquiry
CDCR295685 Human SEPHS2 ORF Clone(NM_012248.2) Inquiry
CDCR372117 Rat Sephs2 ORF Clone(NM_001079889.2) Inquiry
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