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SEC23IP

Official Full Name
SEC23 interacting protein
Organism
Homo sapiens
GeneID
11196
Background
This gene encodes a member of the phosphatidic acid preferring-phospholipase A1 family. The encoded protein is localized to endoplasmic reticulum exit sites and plays a critical role in ER-Golgi transport as part of the multimeric coat protein II complex. An orthologous gene in frogs is required for normal neural crest cell development, suggesting that this gene may play a role in Waardenburg syndrome neural crest defects. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]
Synonyms
P125; P125A; iPLA1A; MSTP053; iPLA1beta;

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