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SCARB2


Official Full Name
scavenger receptor class B member 2
Organism
Homo sapiens
Gene ID
950
Background
The protein encoded by this gene is a type III glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junction obstruction, deafness, and peripheral neuropathy. Further studies in human showed that this protein is a ubiquitously expressed protein and that it is involved in the pathogenesis of HFMD (hand, foot, and mouth disease) caused by enterovirus-71 and possibly by coxsackievirus A16. Mutations in this gene caused an autosomal recessive progressive myoclonic epilepsy-4 (EPM4), also known as action myoclonus-renal failure syndrome (AMRF). Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Feb 2011]
Synonyms
AMRF; EPM4; LGP85; CD36L2; HLGP85; LIMP-2; LIMPII; SR-BII

Cat.No. Product Name Price
SHH402420 shRNA set against Human SCARB2 (NM_005506.3) Inquiry
SHH402424 shRNA set against Mouse SCARB2 (NM_007644.3) Inquiry
SHH402428 shRNA set against Rat SCARB2 (NM_054001.2) Inquiry
SHR207170 shRNA set against Rat Scarb2(NM_054001.2) Inquiry
SHR207192 shRNA set against Mouse Scarb2(NM_007644.3) Inquiry
SHW015418 shRNA set against Danio rerio SCARB2 (NM_173259) Inquiry
Cat.No. Product Name Price
CDFR013703 Rat Scarb2 cDNA Clone(NM_054001.2) Inquiry
MiUTR1M-10428 SCARB2 miRNA 3'UTR clone Inquiry
MiUTR1R-07183 SCARB2 miRNA 3'UTR clone Inquiry
CDCB176893 Danio rerio SCARB2 ORF Clone (NM_173259) Inquiry
CDCB186466 Rabbit SCARB2 ORF clone (XM_002717104.2) Inquiry
CDCH077222 human SCARB2 ORF clone (NM_001204255.1) Inquiry
CDCL186063 Mouse SCARB2 ORF clone(NM_007644.3) Inquiry
CDCR380736 Rat Scarb2 ORF Clone(NM_054001.2) Inquiry
CDCS409612 Human SCARB2 ORF Clone (BC021892) Inquiry
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