Pages
Products

SART1


Official Full Name
spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP
Organism
Homo sapiens
Gene ID
9092
Background
This gene encodes two proteins, the SART1(800) protein expressed in the nucleus of the majority of proliferating cells, and the SART1(259) protein expressed in the cytosol of epithelial cancers. The SART1(259) protein is translated by the mechanism of -1 frameshifting during posttranscriptional regulation; its full-length sequence is not published yet. The two encoded proteins are thought to be involved in the regulation of proliferation. Both proteins have tumor-rejection antigens. The SART1(259) protein possesses tumor epitopes capable of inducing HLA-A2402-restricted cytotoxic T lymphocytes in cancer patients. This SART1(259) antigen may be useful in specific immunotherapy for cancer patients and may serve as a paradigmatic tool for the diagnosis and treatment of patients with atopy. The SART1(259) protein is found to be essential for the recruitment of the tri-snRNP to the pre-spliceosome in the spliceosome assembly pathway. [provided by RefSeq, Jul 2008]
Synonyms
HAF; Ara1; HOMS1; Snu66; SART1259; SNRNP110

Cat.No. Product Name Price
SHH401940 shRNA set against Human SART1 (NM_005146.4) Inquiry
SHH401944 shRNA set against Mouse SART1 (NM_016882.3) Inquiry
SHH401948 shRNA set against Rat SART1 (NM_031596.1) Inquiry
SHR205392 shRNA set against Human SART1(NM_005146.4) Inquiry
SHR205402 shRNA set against Mouse Sart1(NM_016882.3) Inquiry
SHR205428 shRNA set against Rat Sart1(NM_031596.1) Inquiry
SHW006666 shRNA set against Danio rerio SART1 (NM_001002673) Inquiry
Cat.No. Product Name Price
CDFH016913 Human SART1 cDNA Clone(NM_005146.4) Inquiry
CDFR012752 Rat Sart1 cDNA Clone(NM_031596.1) Inquiry
MiUTR1H-09139 SART1 miRNA 3'UTR clone Inquiry
MiUTR1M-10405 SART1 miRNA 3'UTR clone Inquiry
MiUTR1R-07171 SART1 miRNA 3'UTR clone Inquiry
CDCB168141 Danio rerio SART1 ORF Clone (NM_001002673) Inquiry
CDCB181305 Rabbit SART1 ORF clone (XM_008273808.1) Inquiry
CDCH076952 Mouse Sart1 ORF clone (NM_016882.3) Inquiry
CDCR253218 Mouse Sart1 ORF Clone(NM_016882.3) Inquiry
CDCR289691 Human SART1 ORF Clone(NM_005146.4) Inquiry
CDCR379615 Rat Sart1 ORF Clone(NM_031596.1) Inquiry
Quick Inquiry