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SAG


Official Full Name
S-antigen visual arrestin
Organism
Homo sapiens
Gene ID
6295
Background
Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. S-arrestin, also known as S-antigen, is a major soluble photoreceptor protein that is involved in desensitization of the photoactivated transduction cascade. It is expressed in the retina and the pineal gland and inhibits coupling of rhodopsin to transducin in vitro. Additionally, S-arrestin is highly antigenic, and is capable of inducing experimental autoimmune uveoretinitis. Mutations in this gene have been associated with Oguchi disease, a rare autosomal recessive form of night blindness. [provided by RefSeq, Jul 2008]
Synonyms
RP47; RP96; S-AG

Cat.No. Product Name Price
LV24627L human SAG (NM_000541) lentivirus particles Inquiry
Cat.No. Product Name Price
SHH401496 shRNA set against Human Sag (NM_000541.4) Inquiry
SHH401500 shRNA set against Mouse Sag (NM_009118.2) Inquiry
SHR203712 shRNA set against Rat Sag(NM_013023.2) Inquiry
SHR203826 shRNA set against Mouse Sag(NM_009118.2) Inquiry
Cat.No. Product Name Price
CDCH076714 human SAG ORF clone (NM_000541.4) Inquiry
CDFR010828 Rat Sag cDNA Clone(NM_013023.2) Inquiry
MiUTR1M-10385 SAG miRNA 3'UTR clone Inquiry
MiUTR1R-07159 SAG miRNA 3'UTR clone Inquiry
CDCB188524 Rabbit SAG ORF clone (XM_008275274.1) Inquiry
CDCH076718 Mouse Sag ORF clone (NM_009118.2) Inquiry
CDCR377905 Rat Sag ORF Clone(NM_013023.2) Inquiry
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