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RYR2

Official Full Name
ryanodine receptor 2
Organism
Homo sapiens
GeneID
6262
Background
This gene encodes a ryanodine receptor found in cardiac muscle sarcoplasmic reticulum. The encoded protein is one of the components of a calcium channel, composed of a tetramer of the ryanodine receptor proteins and a tetramer of FK506 binding protein 1B proteins, that supplies calcium to cardiac muscle. Mutations in this gene are associated with stress-induced polymorphic ventricular tachycardia and arrhythmogenic right ventricular dysplasia. [provided by RefSeq, Jul 2008]
Synonyms
RyR; ARVC2; ARVD2; RYR-2; VTSIP; VACRDS;

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