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RXRG

Official Full Name
retinoid X receptor gamma
Organism
Homo sapiens
GeneID
6258
Background
This gene encodes a member of the retinoid X receptor (RXR) family of nuclear receptors which are involved in mediating the antiproliferative effects of retinoic acid (RA). This receptor forms dimers with the retinoic acid, thyroid hormone, and vitamin D receptors, increasing both DNA binding and transcriptional function on their respective response elements. This gene is expressed at significantly lower levels in non-small cell lung cancer cells. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jun 2010]
Synonyms
RXRC; NR2B3; RXRgamma; RXR-gamma;

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