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RSPO2

Official Full Name
R-spondin 2
Organism
Homo sapiens
GeneID
340419
Background
This gene encodes a member of the R-spondin family of proteins. These proteins are secreted ligands of leucine-rich repeat containing G protein-coupled receptors that enhance Wnt signaling through the inhibition of ubiquitin E3 ligases. A chromosomal translocation including this locus that results in the formation of a gene fusion has been identified in multiple human cancers. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
Synonyms
HHRRD; TETAMS2; CRISTIN2;

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