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RASSF5

Official Full Name
Ras association domain family member 5
Organism
Homo sapiens
GeneID
83593
Background
This gene is a member of the Ras association domain family. It functions as a tumor suppressor, and is inactivated in a variety of cancers. The encoded protein localizes to centrosomes and microtubules, and associates with the GTP-activated forms of Ras, Rap1, and several other Ras-like small GTPases. The protein regulates lymphocyte adhesion and suppresses cell growth in response to activated Rap1 or Ras. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
RAPL; Maxp1; NORE1; NORE1A; NORE1B; RASSF3;

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