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RASGRP1


Official Full Name
RAS guanyl releasing protein 1
Organism
Homo sapiens
Gene ID
10125
Background
This gene is a member of a family of genes characterized by the presence of a Ras superfamily guanine nucleotide exchange factor (GEF) domain. It functions as a diacylglycerol (DAG)-regulated nucleotide exchange factor specifically activating Ras through the exchange of bound GDP for GTP. It activates the Erk/MAP kinase cascade and regulates T-cells and B-cells development, homeostasis and differentiation. Alternatively spliced transcript variants encoding different isoforms have been identified. Altered expression of the different isoforms of this protein may be a cause of susceptibility to systemic lupus erythematosus (SLE). [provided by RefSeq, Jul 2008]
Synonyms
IMD64; RASGRP; CALDAG-GEFI; CALDAG-GEFII

Cat.No. Product Name Price
SHH390024 shRNA set against Human RASGRP1 (NM_005739.3) Inquiry
SHH390028 shRNA set against Mouse RASGRP1 (NM_011246.2) Inquiry
SHH390032 shRNA set against Rat RASGRP1 (NM_019211.2) Inquiry
SHR166486 shRNA set against Mouse Rasgrp1(NM_011246.2) Inquiry
SHR166504 shRNA set against Rat Rasgrp1(NM_019211.2) Inquiry
SHR166532 shRNA set against Human RASGRP1(NM_001128602.1) Inquiry
Cat.No. Product Name Price
CDCH071868 Mouse Rasgrp1 ORF clone (NM_011246.2) Inquiry
CDFH015946 Human RASGRP1 cDNA Clone(NM_001128602.1) Inquiry
CDFR011507 Rat Rasgrp1 cDNA Clone(NM_019211.2) Inquiry
MiUTR1H-08645 RASGRP1 miRNA 3'UTR clone Inquiry
MiUTR1M-09946 RASGRP1 miRNA 3'UTR clone Inquiry
MiUTR1R-06323 RASGRP1 miRNA 3'UTR clone Inquiry
MiUTR4H-TG07343 RASGRP1 miRNA 3'UTR clone Inquiry
CDCB182311 Rabbit RASGRP1 ORF clone (XM_008269226.1) Inquiry
CDCH071866 human RASGRP1 ORF clone (NM_001128602.1) Inquiry
CDCR378370 Rat Rasgrp1 ORF Clone(NM_019211.2) Inquiry
CDCS407851 Human RASGRP1 ORF Clone (BC109297) Inquiry
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