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RTTN


Official Full Name
rotatin
Organism
Homo sapiens
Gene ID
25914
Background
This gene encodes a large protein whose specific function is unknown. Absence of the orthologous protein in mouse results in embryonic lethality with deficient axial rotation, abnormal differentiation of the neural tube, and randomized looping of the heart tube during development. In human, mutations in this gene are associated with polymicrogyria with seizures. In human fibroblasts this protein localizes at the ciliary basal bodies. Given the intracellular localization of this protein and the phenotypic effects of mutations, this gene is suspected of playing a role in the maintenance of normal ciliary structure which in turn effects the developmental process of left-right organ specification, axial rotation, and perhaps notochord development. [provided by RefSeq, Jan 2013]
Synonyms
MSSP

Cat.No. Product Name Price
SHH400652 shRNA set against Human RTTN (NM_173630.3) Inquiry
SHH400656 shRNA set against Mouse RTTN (NM_175542.3) Inquiry
SHH400660 shRNA set against Rat RTTN (NM_001170436.1) Inquiry
SHR201480 shRNA set against Human RTTN(NM_173630.3) Inquiry
SHR201534 shRNA set against Mouse Rttn(NM_175542.3) Inquiry
SHW003533 shRNA set against Chicken RTTN (NM_001256543) Inquiry
Cat.No. Product Name Price
CDFL011833 Mouse Rttn cDNA Clone(NM_175542.3) Inquiry
MiUTR1H-09077 RTTN miRNA 3'UTR clone Inquiry
MiUTR1M-10333 RTTN miRNA 3'UTR clone Inquiry
CDCB165008 Chicken RTTN ORF Clone (NM_001256543) Inquiry
CDCB191534 Rabbit RTTN ORF clone (XM_008261459.1) Inquiry
CDCR273142 Mouse Rttn ORF Clone(NM_175542.3) Inquiry
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