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RSPO1


Official Full Name
R-spondin 1
Organism
Homo sapiens
Gene ID
284654
Background
This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Synonyms
RSPO; CRISTIN3

Cat.No. Product Name Price
SHH400320 shRNA set against Human RSPO1 (NM_001038633.3) Inquiry
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Cat.No. Product Name Price
CDCS406927 Human RSPO1 ORF Clone (BC114966) Inquiry
CDFR007585 Rat Rspo1 cDNA Clone(NM_001107980.1) Inquiry
CDCB157229 Mouse RSPO1 ORF clone (NM_138683.1) Inquiry
CDCB167860 Danio rerio RSPO1 ORF Clone (NM_001002352) Inquiry
CDCB183333 Rabbit RSPO1 ORF clone (XM_008273651.1) Inquiry
CDCR266345 Mouse Rspo1 ORF Clone(NM_138683.2) Inquiry
CDCR374674 Rat Rspo1 ORF Clone(NM_001107980.1) Inquiry
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