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RSPH10B2


Official Full Name
radial spoke head 10 homolog B2
Organism
Homo sapiens
Gene ID
728194
Background
This gene encodes a protein component of the radial spoke head in flagella and motile cilia. Eukaryotic flagella and motile cilia share a common 9 + 2 structure, in which nine peripheral microtubule doublets (MTDs) surround a central-pair of microtubules (CP), with radial spokes connecting the MTDs to the CP. The radial spoke is a multi-protein complex that works as a mechanochemical transducer between the CP and the MTDs. The radial spoke contributes to the regulation of the activity of dynein motors, and thus to flagellar motility. PMID: 22754630 provides a good review of radial spokes. [provided by RefSeq, Jul 2017]
Synonyms
EST1B; SMG-5; LPTSRP1; LPTS-RP1

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SHH400264 shRNA set against Human RSPH10B2 (NM_001099697.1) Inquiry
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CDFH016754 Human RSPH10B2 cDNA Clone(NM_001099697.1) Inquiry
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