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RNF43


Official Full Name
ring finger protein 43
Organism
Homo sapiens
Gene ID
54894
Background
The protein encoded by this gene is a RING-type E3 ubiquitin ligase and is predicted to contain a transmembrane domain, a protease-associated domain, an ectodomain, and a cytoplasmic RING domain. This protein is thought to negatively regulate Wnt signaling, and expression of this gene results in an increase in ubiquitination of frizzled receptors, an alteration in their subcellular distribution, resulting in reduced surface levels of these receptors. Mutations in this gene have been reported in multiple tumor cells, including colorectal and endometrial cancers. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2015]
Synonyms
URCC; SSPCS; RNF124

Cat.No. Product Name Price
SHH397372 shRNA set against Human RNF43 (NM_017763.4) Inquiry
SHH397376 shRNA set against Mouse RNF43 (NM_172448.3) Inquiry
SHH397381 shRNA set against Rat RNF43 (NM_001135921.1) Inquiry
SHR187386 shRNA set against Mouse Rnf43(NM_172448.3) Inquiry
SHR187464 shRNA set against Human RNF43(NM_017763.4) Inquiry
Cat.No. Product Name Price
CDFL011623 Mouse Rnf43 cDNA Clone(NM_172448.3) Inquiry
CDFR010244 Rat Rnf43 cDNA Clone(NM_001135921.1) Inquiry
MiUTR1H-08905 RNF43 miRNA 3'UTR clone Inquiry
MiUTR1M-10184 RNF43 miRNA 3'UTR clone Inquiry
CDCB185043 Rabbit RNF43 ORF clone (XM_002719265.2) Inquiry
CDCH074690 human RNF43 ORF clone (NM_017763.4) Inquiry
CDCR271009 Mouse Rnf43 ORF Clone(NM_172448.3) Inquiry
CDCR377157 Rat Rnf43 ORF Clone(NM_001135921.1) Inquiry
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