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RNASEH1


Official Full Name
ribonuclease H1
Organism
Homo sapiens
Gene ID
246243
Background
This gene encodes an endonuclease that specifically degrades the RNA of RNA-DNA hybrids and plays a key role in DNA replication and repair. Alternate in-frame start codon initiation results in the production of alternate isoforms that are directed to the mitochondria or to the nucleus. The production of the mitochondrial isoform is modulated by an upstream open reading frame (uORF). Mutations in this gene have been found in individuals with progressive external ophthalmoplegia with mitochondrial DNA deletions, autosomal recessive 2. Alternative splicing results in additional coding and non-coding transcript variants. Pseudogenes of this gene have been defined on chromosomes 2 and 17. [provided by RefSeq, Jul 2017]
Synonyms
RNH1; H1RNA; PEOB2

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SHH396364 shRNA set against Mouse Rnaseh1 (NM_011275.2) Inquiry
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Cat.No. Product Name Price
CDCB190500 Rabbit RNASEH1 ORF clone (XM_008274552.1) Inquiry
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CDFR002824 Rat Rnaseh1 cDNA Clone(NM_001013097.1) Inquiry
MiUTR1H-08861 RNASEH1 miRNA 3'UTR clone Inquiry
MiUTR1R-06981 RNASEH1 miRNA 3'UTR clone Inquiry
CDCB166974 Chicken RNASEH1 ORF Clone (NM_204998) Inquiry
CDCB168130 Danio rerio RNASEH1 ORF Clone (NM_001002659) Inquiry
CDCB175747 Danio rerio RNASEH1 ORF Clone (NM_001285828) Inquiry
CDCH397594 Mouse RNASEH1 ORF clone(NM_011275.2) Inquiry
CDCR284454 Human RNASEH1 ORF Clone(NM_002936.3) Inquiry
CDCR369824 Rat Rnaseh1 ORF Clone(NM_001013097.1) Inquiry
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