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Ren2

Official Full Name
renin 2 tandem duplication of Ren1
Organism
Mus musculus
GeneID
19702
Background
Enables endopeptidase activity. Acts upstream of or within with a negative effect on gene expression. Acts upstream of or within positive regulation of blood pressure. Located in extracellular space. Is expressed in several structures, including adrenal medulla; embryo mesenchyme; medulla oblongata alar plate mantle layer; metanephros; and submandibular gland. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (renin). [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
Ren2; Ren; Rnr; Rn-2; Ren-2; Ren-B;

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