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RELB

Official Full Name
RELB proto-oncogene, NF-kB subunit
Organism
Homo sapiens
GeneID
5971
Background
Enables RNA polymerase II cis-regulatory region sequence-specific DNA binding activity and protein kinase binding activity. Involved in lymphocyte differentiation and negative regulation of interferon-beta production. Located in several cellular components, including centrosome; chromatin; and nucleoplasm. Part of nucleus and transcription repressor complex. Implicated in breast cancer and immunodeficiency 53. Biomarker of breast cancer and transitional cell carcinoma. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
IREL; I-REL; IMD53; REL-B;

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