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RB1


Official Full Name
RB transcriptional corepressor 1
Organism
Homo sapiens
Gene ID
5925
Background
The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma. [provided by RefSeq, Jul 2008]
Synonyms
RB; pRb; OSRC; pp110; p105-Rb; PPP1R130; p110-RB1

Cat.No. Product Name Price
SHH390308 shRNA set against Rat RB1 (NM_017045.1) Inquiry
SHR167568 shRNA set against Rat Rb1(NM_017045.1) Inquiry
SHW004932 shRNA set against Chicken RB1 (NM_204419) Inquiry
SHH390300 shRNA set against Human RB1 (NM_000321.2) Inquiry
SHR167586 shRNA set against Human RB1(NM_000321.2) Inquiry
SHW010742 shRNA set against Danio rerio RB1 (NM_001077780) Inquiry
Cat.No. Product Name Price
MiUTR1H-08661 RB1 miRNA 3'UTR clone Inquiry
MiUTR1R-06335 RB1 miRNA 3'UTR clone Inquiry
SKO0245 RB1 Validated sgRNA vector Inquiry
CDCB166407 Chicken RB1 ORF Clone (NM_204419) Inquiry
CDCB172217 Danio rerio RB1 ORF Clone (NM_001077780) Inquiry
CDCB183453 Rabbit RB1 ORF clone (XM_002720723.2) Inquiry
CDCH396448 Rat RB1 ORF clone(NM_017045.1) Inquiry
CDCL185943 Human RB1 ORF clone(NM_000321.2) Inquiry
CDCS405582 Human RB1 ORF Clone (BC039060) Inquiry
Cat.No. Product Name Price
CC-1196 RB1 Easy KO Kit Inquiry
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