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RAD17


Official Full Name
RAD17 checkpoint clamp loader component
Organism
Homo sapiens
Gene ID
5884
Background
The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs. This protein binds to chromatin prior to DNA damage and is phosphorylated by the checkpoint kinase ATR following damage. This protein recruits the RAD1-RAD9-HUS1 checkpoint protein complex onto chromatin after DNA damage, which may be required for its phosphorylation. The phosphorylation of this protein is required for the DNA-damage-induced cell cycle G2 arrest, and is thought to be a critical early event during checkpoint signaling in DNA-damaged cells. Multiple alternatively spliced transcript variants of this gene, which encode four distinct protein isoforms, have been reported. Two pseudogenes, located on chromosomes 7 and 13, have been identified. [provided by RefSeq, Jul 2013]
Synonyms
CCYC; R24L; RAD24; HRAD17; RAD17SP

Cat.No. Product Name Price
SHH388892 shRNA set against Human RAD17 (NM_002873.1) Inquiry
SHH388896 shRNA set against Mouse RAD17 (NM_011233.2) Inquiry
SHH388900 shRNA set against Rat RAD17 (NM_001024778.1) Inquiry
SHR161358 shRNA set against Human RAD17(NM_133339.1) Inquiry
SHR161376 shRNA set against Human RAD17(NM_002873.1) Inquiry
SHR161394 shRNA set against Human RAD17(NM_133340.1) Inquiry
SHR161412 shRNA set against Mouse Rad17(NM_001044371.1) Inquiry
SHR161430 shRNA set against Human RAD17(NM_133341.1) Inquiry
SHR161448 shRNA set against Mouse Rad17(NM_011233.2) Inquiry
SHR161498 shRNA set against Rat Rad17(NM_001024778.1) Inquiry
SHW006080 shRNA set against Chicken RAD17 (NM_213584) Inquiry
SHW006657 shRNA set against Danio rerio RAD17 (NM_001002661) Inquiry
Cat.No. Product Name Price
CDFG007706 Human RAD17 cDNA Clone(NM_133341.1) Inquiry
CDFG007710 Human RAD17 cDNA Clone(NM_133342.1) Inquiry
CDFG007711 Human RAD17 cDNA Clone(NM_133344.1) Inquiry
CDFH015809 Human RAD17 cDNA Clone(NM_002873.1) Inquiry
CDFH015810 Human RAD17 cDNA Clone(NM_002873.1) Inquiry
CDFR003118 Rat Rad17 cDNA Clone(NM_001024778.1) Inquiry
MiUTR1H-08592 RAD17 miRNA 3'UTR clone Inquiry
CDFG007709 Human RAD17 cDNA Clone(NM_133343.1) Inquiry
MiUTR1H-08593 RAD17 miRNA 3'UTR clone Inquiry
MiUTR1M-09883 RAD17 miRNA 3'UTR clone Inquiry
MiUTR1R-06289 RAD17 miRNA 3'UTR clone Inquiry
MiUTR3H-05697 RAD17 miRNA 3'UTR clone Inquiry
MiUTR3H-05698 RAD17 miRNA 3'UTR clone Inquiry
MiUTR3H-05701 RAD17 miRNA 3'UTR clone Inquiry
MiUTR3H-05702 RAD17 miRNA 3'UTR clone Inquiry
MiUTR1M-09882 RAD17 miRNA 3'UTR clone Inquiry
CDFG007708 Human RAD17 cDNA Clone(NM_133339.1) Inquiry
MiUTR3H-05704 RAD17 miRNA 3'UTR clone Inquiry
CDFG007705 Human RAD17 cDNA Clone(NM_133340.1) Inquiry
CDFG007704 Human RAD17 cDNA Clone(NM_133338.1) Inquiry
MiUTR3H-05703 RAD17 miRNA 3'UTR clone Inquiry
CDCB168132 Danio rerio RAD17 ORF Clone (NM_001002661) Inquiry
CDCB193803 Rabbit RAD17 ORF clone (XM_008262310.1) Inquiry
CDCH071072 human RAD17 ORF clone (NM_002873.1) Inquiry
CDCH071074 human RAD17 ORF clone (NM_133340.1) Inquiry
CDCH071076 human RAD17 ORF clone (NM_133339.1) Inquiry
CDCH071078 human RAD17 ORF clone (NM_133341.1) Inquiry
CDCL185932 Mouse Rad17 ORF clone(NM_001044371.1) Inquiry
CDCR249987 Mouse Rad17 ORF Clone(NM_011233.2) Inquiry
CDCR316007 Human RAD17 ORF Clone(NM_133342.1) Inquiry
CDCR316009 Human RAD17 ORF Clone(NM_133343.1) Inquiry
CDCR316011 Human RAD17 ORF Clone(NM_133344.1) Inquiry
CDCR370723 Rat Rad17 ORF Clone(NM_001024778.1) Inquiry
CDCS411017 Human RAD17 ORF Clone (BC032304) Inquiry
CDCL185931 Human Rad17 ORF clone(NM_133338.1) Inquiry
CDCB167555 Chicken RAD17 ORF Clone (NM_213584) Inquiry
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