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RAB11FIP2

Official Full Name
RAB11 family interacting protein 2 (class I)
Background
A Rab11 effector binding preferentially phosphatidylinositol 3,4,5-trisphosphate (PtdInsP3) and phosphatidic acid (PA) and acting in the regulation of the transport of vesicles from the endosomal recycling compartment (ERC) to the plasma membrane. Involved in insulin granule exocytosis. Also involved in receptor-mediated endocytosis and membrane trafficking of recycling endosomes, probably originating from clathrin-coated vesicles. Required in a complex with MYO5B and RAB11 for the transport of NPC1L1 to the plasma membrane. Also acts as a regulator of cell polarity.
Synonyms
RAB11FIP2; RAB11 family interacting protein 2 (class I); nRip11; Rab11-FIP2; rab11 family-interacting protein 2; RAB11-FIP2 long isoform

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