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PTPRK


Official Full Name
protein tyrosine phosphatase receptor type K
Organism
Homo sapiens
Gene ID
5796
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation. [provided by RefSeq, Jul 2008]
Synonyms
R-PTP-kappa

Cat.No. Product Name Price
SHH386760 shRNA set against Mouse PTPRK (NM_008983.2) Inquiry
SHH386764 shRNA set against Rat PTPRK (NM_001029902.2) Inquiry
SHR153472 shRNA set against Rat Ptprk(NM_001029902.2) Inquiry
SHR153490 shRNA set against Mouse Ptprk(NM_008983.2) Inquiry
Cat.No. Product Name Price
CDFH015588 Human PTPRK cDNA Clone(NM_001135648.1) Inquiry
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MiUTR1R-06211 PTPRK miRNA 3'UTR clone Inquiry
MiUTR3H-05072 PTPRK miRNA 3'UTR clone Inquiry
MiUTR3H-05073 PTPRK miRNA 3'UTR clone Inquiry
CDCB193644 Rabbit PTPRK ORF clone (XM_008263481.1) Inquiry
CDCH069906 human PTPRK ORF clone (NM_002844.3) Inquiry
CDCH069908 human PTPRK ORF clone (NM_001135648.1) Inquiry
CDCR246496 Mouse Ptprk ORF Clone(NM_008983.2) Inquiry
CDCR371151 Rat Ptprk ORF Clone(NM_001029902.2) Inquiry
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