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PTPRJ


Official Full Name
protein tyrosine phosphatase receptor type J
Organism
Homo sapiens
Gene ID
5795
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes, including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region containing five fibronectin type III repeats, a single transmembrane region, and a single intracytoplasmic catalytic domain, and thus represents a receptor-type PTP. This protein is present in all hematopoietic lineages, and was shown to negatively regulate T cell receptor signaling possibly through interfering with the phosphorylation of Phospholipase C Gamma 1 and Linker for Activation of T Cells. This protein can also dephosphorylate the PDGF beta receptor, and may be involved in UV-induced signal transduction. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Synonyms
DEP1; SCC1; CD148; THC10; HPTPeta; R-PTP-J; HPTP eta; R-PTP-ETA

Cat.No. Product Name Price
SHH386752 shRNA set against Rat PTPRJ (NM_017269.2) Inquiry
SHH386744 shRNA set against Human PTPRJ (NM_002843.3) Inquiry
SHH386748 shRNA set against Mouse PTPRJ (NM_008982.5) Inquiry
SHR153336 shRNA set against Human PTPRJ(NM_002843.3) Inquiry
SHR153354 shRNA set against Mouse Ptprj(NM_001135657.1) Inquiry
SHW005132 shRNA set against Chicken PTPRJ (NM_204621) Inquiry
Cat.No. Product Name Price
CDFG019547 Mouse Ptprj cDNA Clone(NM_001135657.1) Inquiry
CDFH015585 Human PTPRJ cDNA Clone(NM_001098503.1) Inquiry
CDFL011061 Mouse Ptprj cDNA Clone(NM_008982.5) Inquiry
CDFR011318 Rat Ptprj cDNA Clone(NM_017269.2) Inquiry
MiUTR1H-08477 PTPRJ miRNA 3'UTR clone Inquiry
MiUTR1M-09774 PTPRJ miRNA 3'UTR clone Inquiry
MiUTR3H-03739 PTPRJ miRNA 3'UTR clone Inquiry
CDCB166607 Chicken PTPRJ ORF Clone (NM_204621) Inquiry
CDCB189134 Rabbit PTPRJ ORF clone (XM_008272471.1) Inquiry
CDCH069896 human PTPRJ ORF clone (NM_001098503.1) Inquiry
CDCH069900 Mouse Ptprj ORF clone (NM_001135657.1) Inquiry
CDCH069902 Mouse Ptprj ORF clone (NM_008982.5) Inquiry
CDCL185914 Human PTPRJ ORF clone(NM_002843.3) Inquiry
CDCR378332 Rat Ptprj ORF Clone(NM_017269.2) Inquiry
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