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PTPRF


Official Full Name
protein tyrosine phosphatase receptor type F
Organism
Homo sapiens
Gene ID
5792
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
Synonyms
LAR; BNAH2

Cat.No. Product Name Price
SHH220002 shRNA set against Mouse Ptprf(NM_011213.2) Inquiry
SHH386708 shRNA set against Human PTPRF (NM_002840.3) Inquiry
SHH386712 shRNA set against Mouse PTPRF (NM_011213.2) Inquiry
SHH386716 shRNA set against Rat PTPRF (NM_019249.1) Inquiry
Cat.No. Product Name Price
CDFH015579 Human PTPRF cDNA Clone(NM_002840.3) Inquiry
MiUTR1M-09771 PTPRF miRNA 3'UTR clone Inquiry
MiUTR1H-08476 PTPRF miRNA 3'UTR clone Inquiry
MiUTR1H-08475 PTPRF miRNA 3'UTR clone Inquiry
CDFR011542 Rat Ptprf cDNA Clone(NM_019249.1) Inquiry
CDFL011058 Mouse Ptprf cDNA Clone(NM_011213.2) Inquiry
CDFH015581 Human PTPRF cDNA Clone(NM_002840.3) Inquiry
MiUTR1R-06209 PTPRF miRNA 3'UTR clone Inquiry
SKO0729 PTPRF Validated sgRNA vector Inquiry
CDCL149688 Mouse Ptprf ORF clone (NM_011213.2) Inquiry
CDFG007587 Human PTPRF cDNA Clone(NM_130440.2) Inquiry
CDCS411004 Human PTPRF ORF Clone (BC012102) Inquiry
CDCS411003 Human PTPRF ORF Clone (BC048416) Inquiry
CDCR378545 Rat Ptprf ORF Clone(NM_019249.1) Inquiry
CDCR315457 Human PTPRF ORF Clone(NM_130440.2) Inquiry
CDCR284196 Human PTPRF ORF Clone(NM_002840.3) Inquiry
CDCB185417 Rabbit PTPRF ORF clone (XM_008265399.1) Inquiry
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