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PTPN6


Official Full Name
protein tyrosine phosphatase non-receptor type 6
Organism
Homo sapiens
Gene ID
5777
Background
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. N-terminal part of this PTP contains two tandem Src homolog (SH2) domains, which act as protein phospho-tyrosine binding domains, and mediate the interaction of this PTP with its substrates. This PTP is expressed primarily in hematopoietic cells, and functions as an important regulator of multiple signaling pathways in hematopoietic cells. This PTP has been shown to interact with, and dephosphorylate a wide spectrum of phospho-proteins involved in hematopoietic cell signaling. Multiple alternatively spliced variants of this gene, which encode distinct isoforms, have been reported. [provided by RefSeq, Jul 2008]
Synonyms
HCP; HCPH; SHP1; SHP-1; HPTP1C; PTP-1C; SHP-1L; SH-PTP1

Cat.No. Product Name Price
SHH386608 shRNA set against Rat Ptpn6 (NM_053908.1) Inquiry
SHH219930 shRNA set against Mouse Ptpn6(NM_013545.2) Inquiry
SHH219948 shRNA set against Mouse Ptpn6(NM_001077705.1) Inquiry
SHH219966 shRNA set against Human PTPN6(NM_080548.4) Inquiry
SHH219984 shRNA set against Human PTPN6(NM_002831.5) Inquiry
SHH386600 shRNA set against Human Ptpn6 (NM_002831.5) Inquiry
SHH386604 shRNA set against Mouse Ptpn6 (NM_013545.2) Inquiry
SHR152568 shRNA set against Rat Ptpn6(NM_053908.1) Inquiry
SHW002073 shRNA set against Chicken PTPN6 (NM_001031484) Inquiry
SHW016212 shRNA set against Danio rerio PTPN6 (NM_199960) Inquiry
Cat.No. Product Name Price
CDFG007332 Human PTPN6 cDNA Clone(NM_080549.3) Inquiry
MiUTR1R-06203 PTPN6 miRNA 3'UTR clone Inquiry
MiUTR1M-09764 PTPN6 miRNA 3'UTR clone Inquiry
MiUTR1M-09763 PTPN6 miRNA 3'UTR clone Inquiry
MiUTR1H-08470 PTPN6 miRNA 3'UTR clone Inquiry
MiUTR1H-08469 PTPN6 miRNA 3'UTR clone Inquiry
CDFR013622 Rat Ptpn6 cDNA Clone(NM_053908.1) Inquiry
CDFG018569 Mouse Ptpn6 cDNA Clone(NM_001077705.1) Inquiry
MiUTR3H-01887 PTPN6 miRNA 3'UTR clone Inquiry
SKO0728 PTPN6 Validated sgRNA vector Inquiry
CDCR314843 Human PTPN6 ORF Clone(NM_080549.3) Inquiry
CDCR380505 Rat Ptpn6 ORF Clone(NM_053908.1) Inquiry
CDCL185910 Mouse PTPN6 ORF clone(NM_001077705.1) Inquiry
CDCL185909 Human PTPN6 ORF clone(NM_002831.5) Inquiry
CDCL149683 Human Ptpn6 ORF clone (NM_013545.2) Inquiry
CDCB188651 Rabbit PTPN6 ORF clone (XM_008259766.1) Inquiry
CDCB177687 Danio rerio PTPN6 ORF Clone (NM_199960) Inquiry
CDCS410997 Human PTPN6 ORF Clone (BC002523) Inquiry
CDCB163548 Chicken PTPN6 ORF Clone (NM_001031484) Inquiry
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