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PSMD4


Official Full Name
proteasome 26S subunit ubiquitin receptor, non-ATPase 4
Organism
Homo sapiens
Gene ID
5710
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the non-ATPase subunits of the 19S regulator lid. Pseudogenes have been identified on chromosomes 10 and 21. [provided by RefSeq, Jul 2008]
Synonyms
AF; ASF; S5A; AF-1; MCB1; Rpn10; pUB-R5

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SHH385444 shRNA set against Human PSMD4 (NM_002810.2) Inquiry
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Cat.No. Product Name Price
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MiUTR1H-08390 PSMD4 miRNA 3'UTR clone Inquiry
MiUTR1M-09703 PSMD4 miRNA 3'UTR clone Inquiry
MiUTR1R-06157 PSMD4 miRNA 3'UTR clone Inquiry
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CDCR284120 Human PSMD4 ORF Clone(NM_002810.2) Inquiry
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