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PSMC6


Official Full Name
proteasome 26S subunit, ATPase 6
Organism
Homo sapiens
Gene ID
5706
Background
The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes one of the ATPase subunits, a member of the triple-A family of ATPases which have a chaperone-like activity. Pseudogenes have been identified on chromosomes 8 and 12. [provided by RefSeq, Jul 2008]
Synonyms
p42; RPT5; SUG2

Cat.No. Product Name Price
SHH385336 shRNA set against Human PSMC6 (NM_002806.3) Inquiry
SHH385340 shRNA set against Mouse PSMC6 (NM_025959.3) Inquiry
SHH385344 shRNA set against Rat PSMC6 (NM_001100509.1) Inquiry
SHR148116 shRNA set against Mouse Psmc6(NM_025959.3) Inquiry
SHW000575 shRNA set against Chicken PSMC6 (NM_001006494) Inquiry
SHW007009 shRNA set against Danio rerio PSMC6 (NM_001003832) Inquiry
Cat.No. Product Name Price
CDCH069098 human PSMC6 ORF clone (NM_002806.3) Inquiry
CDCR257907 Mouse Psmc6 ORF Clone(NM_025959.3) Inquiry
CDFH015383 Human PSMC6 cDNA Clone(NM_002806.3) Inquiry
CDFR005254 Rat Psmc6 cDNA Clone(NM_001100509.1) Inquiry
MiUTR1M-09696 PSMC6 miRNA 3'UTR clone Inquiry
MiUTR3H-05250 PSMC6 miRNA 3'UTR clone Inquiry
CDCB159373 Human PSMC6 ORF clone (BC005390) Inquiry
CDCB162050 Chicken PSMC6 ORF Clone (NM_001006494) Inquiry
CDCB168484 Danio rerio PSMC6 ORF Clone (NM_001003832) Inquiry
CDCB185558 Rabbit PSMC6 ORF clone (XM_008269661.1) Inquiry
CDCR372297 Rat Psmc6 ORF Clone(NM_001100509.1) Inquiry
CDCS410974 Human PSMC6 ORF Clone (BC005390) Inquiry
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