Pages
Products

PSMB3


Official Full Name
proteasome 20S subunit beta 3
Organism
Homo sapiens
Gene ID
5691
Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. The 26 S proteasome may be involved in trinucleotide repeat expansion, a phenomenon which is associated with many hereditary neurological diseases. Pseudogenes have been identified on chromosomes 2 and 12. Alternative splicing results in multiple transcript variants [provided by RefSeq, Sep 2013]
Synonyms
HC10-II

Cat.No. Product Name Price
SHH385180 shRNA set against Human PSMB3 (NM_002795.2) Inquiry
SHH385184 shRNA set against Mouse PSMB3 (NM_011971.4) Inquiry
SHH385188 shRNA set against Rat PSMB3 (NM_017285.1) Inquiry
SHR147462 shRNA set against Mouse Psmb3(NM_011971.4) Inquiry
SHR147522 shRNA set against Human PSMB3(NM_002795.2) Inquiry
SHR147540 shRNA set against Rat Psmb3(NM_017285.1) Inquiry
SHW012946 shRNA set against Danio rerio PSMB3 (NM_001129823) Inquiry
Cat.No. Product Name Price
CDFH015361 Human PSMB3 cDNA Clone(NM_002795.2) Inquiry
CDFH015362 Human PSMB3 cDNA Clone(NM_002795.2) Inquiry
CDFH015363 Human PSMB3 cDNA Clone(NM_002795.2) Inquiry
CDFR011333 Rat Psmb3 cDNA Clone(NM_017285.1) Inquiry
MiUTR1H-08379 PSMB3 miRNA 3'UTR clone Inquiry
MiUTR1M-09687 PSMB3 miRNA 3'UTR clone Inquiry
MiUTR1R-06143 PSMB3 miRNA 3'UTR clone Inquiry
CDCB174421 Danio rerio PSMB3 ORF Clone (NM_001129823) Inquiry
CDCB186797 Rabbit PSMB3 ORF clone (XM_002719331.2) Inquiry
CDCR283767 Human PSMB3 ORF Clone(NM_002795.2) Inquiry
CDCR378347 Rat Psmb3 ORF Clone(NM_017285.1) Inquiry
CDCS410961 Human PSMB3 ORF Clone (BC013008) Inquiry
Quick Inquiry