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PRSS2


Official Full Name
serine protease 2
Organism
Homo sapiens
Gene ID
5645
Background
This gene belongs to the trypsin family of serine proteases and encodes anionic trypsinogen. It is part of a cluster of trypsinogen genes that are located within the T cell receptor beta locus. Enzymes of this family cleave peptide bonds that follow lysine or arginine residues. This protein is found at high levels in pancreatic juice and its upregulation is a characteristic feature of pancreatitis. This protein has also been found to activate pro-urokinase in ovarian tumors, suggesting a function in tumor invasion. In addition, this enzyme is able to cleave across the type II collagen triple helix in rheumatoid arthritis synovitis tissue, potentially participating in the degradation of type II collagen-rich cartilage matrix. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Jan 2015]
Synonyms
TRY2; TRY8; TRYP2

Cat.No. Product Name Price
LV22835L human PRSS2 (NM_002770) lentivirus particles Inquiry
Cat.No. Product Name Price
SHH384368 shRNA set against Mouse PRSS2 (NM_009430.2) Inquiry
SHW005879 shRNA set against Chicken PRSS2 (NM_205384) Inquiry
SHH384364 shRNA set against Human PRSS2 (NM_031948.3) Inquiry
SHH384372 shRNA set against Rat PRSS2 (NM_012729.1) Inquiry
SHR144064 shRNA set against Mouse Prss2(NM_009430.2) Inquiry
SHR144634 shRNA set against Rat Prss2(NM_012729.1) Inquiry
SHR144670 shRNA set against Human PRSS2(NM_002770.2) Inquiry
Cat.No. Product Name Price
CDFH015277 Human PRSS2 cDNA Clone(NM_002770.2) Inquiry
CDFL010891 Mouse Prss2 cDNA Clone(NM_009430.2) Inquiry
CDFR010542 Rat Prss2 cDNA Clone(NM_012729.1) Inquiry
MiUTR1H-08337 PRSS2 miRNA 3'UTR clone Inquiry
MiUTR1M-09647 PRSS2 miRNA 3'UTR clone Inquiry
MiUTR1R-06113 PRSS2 miRNA 3'UTR clone Inquiry
CDCB156332 Cynomolgus PRSS2 ORF clone (NM_001047120.1) Inquiry
CDCB167354 Chicken PRSS2 ORF Clone (NM_205384) Inquiry
CDCL185871 Human PRSS2 ORF clone(NM_002770.2) Inquiry
CDCR377589 Rat Prss2 ORF Clone(NM_012729.1) Inquiry
CDCS410949 Human PRSS2 ORF Clone (BC030260) Inquiry
CDCS410950 Human PRSS2 ORF Clone (BC103997) Inquiry
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