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PRPF19

Official Full Name
pre-mRNA processing factor 19
Organism
Homo sapiens
GeneID
27339
Background
Enables identical protein binding activity and ubiquitin-ubiquitin ligase activity. Involved in several processes, including DNA damage checkpoint signaling; mRNA splicing, via spliceosome; and protein K63-linked ubiquitination. Acts upstream of or within protein polyubiquitination. Located in cytoplasm; nuclear lumen; and site of double-strand break. Part of Prp19 complex and U2-type catalytic step 2 spliceosome. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
PSO4; SNEV; PRP19; UBOX4; hPSO4; NMP200;

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