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PPP3CB

Official Full Name
protein phosphatase 3 catalytic subunit beta
Organism
Homo sapiens
GeneID
5532
Background
Enables several functions, including calmodulin binding activity; calmodulin-dependent protein phosphatase activity; and protein phosphatase 2B binding activity. Involved in several processes, including calcineurin-NFAT signaling cascade; positive regulation of lysosome organization; and positive regulation of protein localization to nucleus. Located in cytoplasm. Part of calcineurin complex. Implicated in aortic valve stenosis. Biomarker of focal segmental glomerulosclerosis and schizophrenia. [provided by Alliance of Genome Resources, Feb 2025]
Synonyms
CNA2; CALNB; CALNA2; PP2Bbeta;

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