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PPP2R2B


Official Full Name
protein phosphatase 2 regulatory subunit Bbeta
Organism
Homo sapiens
Gene ID
5521
Background
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a beta isoform of the regulatory subunit B55 subfamily. Defects in this gene cause autosomal dominant spinocerebellar ataxia 12 (SCA12), a disease caused by degeneration of the cerebellum, sometimes involving the brainstem and spinal cord, and in resulting in poor coordination of speech and body movements. Multiple alternatively spliced variants, which encode different isoforms, have been identified for this gene. The 5' UTR of some of these variants includes a CAG trinucleotide repeat sequence (7-28 copies) that can be expanded to 55-78 copies in cases of SCA12. [provided by RefSeq, Jul 2016]
Synonyms
PR52B; SCA12; B55BETA; PR55BETA; PP2ABBETA; PP2APR55B; PR2ABBETA; PR55-BETA; PP2AB55BETA; PR2AB55BETA; PP2APR55BETA; PR2APR55BETA

Cat.No. Product Name Price
SHH381396 shRNA set against Human PPP2R2B (NM_181678.2) Inquiry
SHH381400 shRNA set against Mouse PPP2R2B (NM_028392.2) Inquiry
SHH381404 shRNA set against Rat PPP2R2B (NM_022209.2) Inquiry
SHR134408 shRNA set against Rat Ppp2r2b(NM_022209.2) Inquiry
SHR134416 shRNA set against Human PPP2R2B(NM_004576.2) Inquiry
SHR134598 shRNA set against Mouse Ppp2r2b(NM_027531.1) Inquiry
SHR134644 shRNA set against Mouse Ppp2r2b(NM_028392.2) Inquiry
Cat.No. Product Name Price
CDFH014933 Human PPP2R2B cDNA Clone(NM_004576.2) Inquiry
MiUTR3H-06721 PPP2R2B miRNA 3'UTR clone Inquiry
MiUTR3H-06720 PPP2R2B miRNA 3'UTR clone Inquiry
MiUTR3H-06719 PPP2R2B miRNA 3'UTR clone Inquiry
MiUTR3H-06717 PPP2R2B miRNA 3'UTR clone Inquiry
MiUTR1R-06015 PPP2R2B miRNA 3'UTR clone Inquiry
MiUTR1M-09512 PPP2R2B miRNA 3'UTR clone Inquiry
MiUTR1M-09511 PPP2R2B miRNA 3'UTR clone Inquiry
MiUTR1H-08192 PPP2R2B miRNA 3'UTR clone Inquiry
CDFR011894 Rat Ppp2r2b cDNA Clone(NM_022209.2) Inquiry
MiUTR3H-06723 PPP2R2B miRNA 3'UTR clone Inquiry
CDFH014932 Human PPP2R2B cDNA Clone(NM_001127381.1) Inquiry
MiUTR3H-06722 PPP2R2B miRNA 3'UTR clone Inquiry
CDCS407795 Human PPP2R2B ORF Clone (BC031790) Inquiry
CDCR378897 Rat Ppp2r2b ORF Clone(NM_022209.2) Inquiry
CDCR348643 Human PPP2R2B ORF Clone(NM_001127381.1) Inquiry
CDCR288371 Human PPP2R2B ORF Clone(NM_004576.2) Inquiry
CDCR261426 Mouse Ppp2r2b ORF Clone(NM_028392.2) Inquiry
CDCH066988 Mouse Ppp2r2b ORF clone (NM_027531.1) Inquiry
CDCH066986 human PPP2R2B ORF clone (NM_181678.2) Inquiry
CDCH066984 human PPP2R2B ORF clone (NM_181676.2) Inquiry
CDCB181111 Rabbit PPP2R2B ORF clone (NM_001195718.1) Inquiry
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