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PPP1R13B

Official Full Name
protein phosphatase 1 regulatory subunit 13B
Organism
Homo sapiens
GeneID
23368
Background
This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor. [provided by RefSeq, Jul 2008]
Synonyms
p85; ASPP1; p53BP2-like;

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