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PPL


Official Full Name
periplakin
Organism
Homo sapiens
Gene ID
5493
Background
The protein encoded by this gene is a component of desmosomes and of the epidermal cornified envelope in keratinocytes. The N-terminal domain of this protein interacts with the plasma membrane and its C-terminus interacts with intermediate filaments. Through its rod domain, this protein forms complexes with envoplakin. This protein may serve as a link between the cornified envelope and desmosomes as well as intermediate filaments. AKT1/PKB, a protein kinase mediating a variety of cell growth and survival signaling processes, is reported to interact with this protein, suggesting a possible role for this protein as a localization signal in AKT1-mediated signaling. [provided by RefSeq, Jul 2008]
Synonyms
Faap20

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LV22398L human PPL (NM_002705) lentivirus particles Inquiry
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SHH380772 shRNA set against Human PPL (NM_002705.4) Inquiry
SHH380776 shRNA set against Mouse PPL (NM_008909.2) Inquiry
SHH380780 shRNA set against Rat PPL (NM_001106976.1) Inquiry
SHR132540 shRNA set against Mouse Ppl(NM_008909.2) Inquiry
SHR132594 shRNA set against Human PPL(NM_002705.4) Inquiry
SHW013110 shRNA set against Danio rerio PPL (NM_001137666) Inquiry
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CDCB191365 Rabbit PPL ORF clone (XM_008249638.1) Inquiry
CDFL010638 Mouse Ppl cDNA Clone(NM_008909.2) Inquiry
CDFR006689 Rat Ppl cDNA Clone(NM_001106976.1) Inquiry
MiUTR1H-08162 PPL miRNA 3'UTR clone Inquiry
MiUTR1M-09474 PPL miRNA 3'UTR clone Inquiry
CDCB174585 Danio rerio PPL ORF Clone (NM_001137666) Inquiry
CDCH066628 Mouse Ppl ORF clone (NM_008909.2) Inquiry
CDCR373582 Rat Ppl ORF Clone(NM_001106976.1) Inquiry
CDCS410913 Human PPL ORF Clone (BC114620) Inquiry
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